Ion-Induced Volume Transition in Gels and Its Role in Biology
Open Access
- 18 February 2021
- Vol. 7 (1), 20
- https://doi.org/10.3390/gels7010020
Abstract
Incremental changes in ionic composition, solvent quality, and temperature can lead to reversible and abrupt structural changes in many synthetic and biopolymer systems. In the biological milieu, this nonlinear response is believed to play an important functional role in various biological systems, including DNA condensation, cell secretion, water flow in xylem of plants, cell resting potential, and formation of membraneless organelles. While these systems are markedly different from one another, a physicochemical framework that treats them as polyelectrolytes, provides a means to interpret experimental results and make in silico predictions. This article summarizes experimental results made on ion-induced volume phase transition in a polyelectrolyte model gel (sodium polyacrylate) and observations on the above-mentioned biological systems indicating the existence of a steep response.Keywords
This publication has 119 references indexed in Scilit:
- Variation of Weak Polyelectrolyte Persistence Length through an Electrostatic Contour LengthMacromolecules, 2012
- Theory of volume transition in polyelectrolyte gels with charge regularizationThe Journal of Chemical Physics, 2012
- Phase transitions in the assembly of multivalent signalling proteinsNature, 2012
- Counterion and pH‐Mediated Structural Changes in Charged Biopolymer GelsMacromolecular Symposia, 2010
- Ionic and pH effects on the osmotic properties and structure of polyelectrolyte gelsJournal of Polymer Science Part B: Polymer Physics, 2008
- Molecular simulation of the swelling of polyelectrolyte gels by monovalent and divalent counterionsThe Journal of Chemical Physics, 2008
- Interplay of ion binding and attraction in DNA condensed by multivalent cationsNucleic Acids Research, 2007
- Polymer gel phase transition in condensation-decondensation of secretory productsPublished by Springer Science and Business Media LLC ,2005
- Cajal Bodies: The First 100 YearsAnnual Review of Cell and Developmental Biology, 2000
- Subaxolemmal filamentous network in the giant nerve fiber of the squid (Loligo pealei L.) and its possible role in excitability.The Journal of cell biology, 1978