Thoracoscopic total laryngo-pharyngo-oesophagectomy for the pharyngoesophageal junction cancer: a single-center experience of multidisciplinary team
- 2 March 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in European Archives Of Oto-Rhino-Laryngology
- Vol. 278 (11), 4509-4517
- https://doi.org/10.1007/s00405-021-06706-8
Abstract
Purpose The aims of this study were to review the surgical experience and evaluate the feasibility of thoracoscopic total laryngo-pharyngo-oesophagectomy by multidisciplinary team in the patients with pharyngoesophageal junction cancer. Methods A total of 31 patients with pharyngoesophageal junction cancer who underwent thoracoscopic total laryngo-pharyngo-oesophagectomy with gastric pull-up reconstruction performed by a collaborative thoracic surgery and otolaryngology surgery team in our department from January 2009 to January 2019 were retrospectively analysed. Surgical experience, Postoperative morbidity, overall survival were evaluated. Results The median age was 62 years old. Among these patients, 20 had hypopharyngeal cancer, 11 had cervical oesophageal cancer. No patients died during the perioperative period, and the median operation time was 4 h 30 min. The mean hospital stay was 13 days. The rate of complications was 32.3%. There were two cases of anastomotic leakage, four cases of moderate pulmonary infection. The median follow-up period was 31 months. Four patients were lost to follow-up in the second and fourth years and were considered to have died at that time. The 3- and 5-year overall survival rates were 52.6% and 31.6%, respectively. Conclusion As a salvage surgery, thoracoscopic total laryngo-pharyngo-oesophagectomy by multidisciplinary team can be performed with an acceptable level of perioperative morbidity and mortality, relatively good recovery, and acceptable survival outcome for patients with pharyngoesophageal junction cancer.Keywords
Funding Information
- Natural Science Foundation of Fujian Province (2020J01953)
- Young and Middle-aged Teachers Scientific Research Project of Education Department ,Fujian Province, China (JAT190212)
This publication has 31 references indexed in Scilit:
- Thoracoscopic esophagectomy in the prone positionSurgical Endoscopy, 2012
- Complication following gastric pull-up reconstruction for advanced hypopharyngeal or cervical esophageal carcinoma: a 20-year review in a Chinese instituteAmerican Journal of Otolaryngology, 2011
- Effect of Concurrent High-Dose Cisplatin Chemotherapy and Conformal Radiotherapy on Cervical Esophageal Cancer SurvivalInternational Journal of Radiation Oncology*Biology*Physics, 2008
- Hypopharyngeal CancerTopics in Magnetic Resonance Imaging, 2007
- A reappraisal of surgical management for squamous cell carcinoma in the pharyngoesophageal junctionJournal of Surgical Oncology, 2006
- Treatment results of radiotherapy for carcinoma of the cervical esophagusActa Oncologica, 2006
- Minimally invasive pharyngo-laryngo-esophagectomy: a salvage procedure for recurrent postcricoid esophageal cancerDiseases of the Esophagus, 2005
- Paratracheal Lymph Node Involvement in Advanced Cancer of the Larynx, Hypopharynx, and Cervical EsophagusThe Laryngoscope, 2003
- Significance of Retropharyngeal Node Dissection at Radical Surgery for Carcinoma of the Hypopharynx and Cervical EsophagusThe Laryngoscope, 2001
- Analysis of the methods of pharyngoesophageal reconstructionHead & Neck Surgery, 1984