ICTV Virus Taxonomy Profile: Hepadnaviridae
Open Access
- 1 January 2020
- journal article
- editorial
- Published by Microbiology Society in Journal of General Virology
- Vol. 101 (6), 571-572
- https://doi.org/10.1099/jgv.0.001415
Abstract
The family Hepadnaviridae comprises small enveloped viruses with a partially double-stranded DNA genome of 3.0-3.4 kb. All family members express three sets of proteins (preC/C, polymerase and preS/S) and replication involves reverse transcription within nucleocapsids in the cytoplasm of hepatocytes. Hepadnaviruses are hepatotropic and infections may be transient or persistent. There are five genera: Parahepadnavirus, Metahepadnavirus, Herpetohepadnavirus, Avihepadnavirus and Orthohepadnavirus. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hepadnaviridae, which is available at ictv.global/report/hepadnaviridae.Keywords
Funding Information
- Wellcome Trust (WT108418AIA)
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