Neonatal management of prenatally suspected coarctation of the aorta
- 11 April 2020
- journal article
- research article
- Published by Wiley in Prenatal Diagnosis
- Vol. 40 (8), 942-948
- https://doi.org/10.1002/pd.5696
Abstract
Objectives (1) To determine the false positive rate among newborns with prenatally suspected CoA within the UCLA Health system, (2) to compare patient and maternal interventions and outcomes between false positive cases and normal controls, and (3) to determine the timing of clinical presentation of CoA. Methods We performed a single‐center, retrospective case control study of all fetuses with suspected isolated CoA who underwent both fetal echocardiographic evaluation and subsequent delivery at UCLA between January 1, 2011 and December 31, 2018. Maternal and neonatal medical records were reviewed for demographic and clinical data, for cases of suspected CoA and for controls. A separate review of our institution's surgical database was performed to identify characteristics of all patients (neonatal and pediatric) with isolated CoA who underwent surgical repair during the same time period. Results Among the 50 fetal cases of isolated suspected CoA who delivered at our institution, 47 patients (94%) were found to be normal (false positives). Compared with normal controls, patients with suspected CoA were more likely to have delayed maternal bonding, delayed feeding, admission to the intensive care unit, performance of neonatal echocardiograms, initiation of IVF and initiation of PGE1, and a longer length of hospital stay. Among the 38 patients undergoing CoA repair at our institution during the study period, 4 patients were prenatally diagnosed and no patient presented clinically with symptoms before 48 hours after delivery. Conclusion Compared with normal controls, patients with prenatally suspected coarctation are more likely to have delayed maternal bonding, delayed feeding, more frequent neonatal echocardiograms, and longer length of hospital stay. Further refinement of neonatal management may improve postnatal care.Funding Information
- Molly and Samuel Kaplan Fellowship (CDI-MSKF-07012019)
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