COVID 19 pandemic has been with us for more than a year now and new insights in pathophysiology and clinical manifestations have emerged. Recent reports have shown that not only is acute COVID a life-threatening disease, but post COVID symptoms are more common than previously thought and may greatly affect quality of life. In this review, we explore the usefulness of regenerative rehabilitation with Mesenchymal Stem Cells (MSC) in post COVID symptoms based on previous knowledge in other medical conditions