宫颈癌是最常见的妇科恶性肿瘤之一，绝大多数宫颈癌的发生发展都有较长时间的癌前病变，但由于各种检测方法和经济条件的限制，多数患者发现时已为中晚期，导致病死率很高，早期发现、诊断明确、及时采取有效措施能预防和终止病情的发展。宫颈癌的诊断方法多种多样，现常用液基细胞学检查(Thinprep cytologic test, TCT)及HPV联合筛查。而肿瘤标志物检测也是常用方法之一，其因客观、无创、便捷而发挥重要作用。肿瘤相关标志物检测对宫颈癌的筛查、辅助诊断、判别类型、评估预后、评价疗效、定位诊断、靶向治疗等均具有重要指导意义。 Cervical cancer is one of the most common gynecological malignancies. Most cervical cancers have long-term precancerous lesions in their occurrence and development. However, due to the limitations of various detection methods and economic conditions, most patients are already in the middle and advanced stages when discovered, leading to a high mortality rate. Early detection, clear diagnosis, and timely effective measures prevent and stop the development of the disease. There are various diagnostic methods for cervical cancer. Liquid-based cytologic test (Thinprep cytologic test, TCT) and HPV combined screening are commonly used. The detection of tumor markers is also one of the commonly used methods, which plays an important role due to its objectiveness, non-invasiveness and convenience. The detection of tumor-related markers has important guiding significance in the screening, auxiliary diagnosis, type identification, prognosis evaluation, evaluation of curative effect, localized diagnosis, and targeted therapy of cervical cancer.