Marine Algae Polysaccharides - a Promising Means of Pathogenetic Therapy of Infectious Diarrhea
- 21 November 2020
- journal article
- Published by Publishing House OKI in Antibiotics and Chemotherapy
- Vol. 65 (7-8), 42-51
- https://doi.org/10.37489/0235-2990-2020-65-7-8-42-51
Abstract
The review considers the current views on pathogenesis and therapeutic targets in infectious diarrhea that develops as a result of exposure of enterocytes to viruses or bacterial toxins. The main methods of infectious diarrhea treatment and disadvantages of standard therapy are described. Modern data on the biological activity (bactericidal/bacteriostatic, antiviral, anti-biofilm, antiinflammatory, immunomodulatory, and antioxidant properties) of marine algae polysaccharides are presented. The possibilities of using seaweed polysaccharides as the basis of medicines, dietary supplements and functional food products for the prevention and treatment of infectious diarrhea are evaluated.Keywords
This publication has 61 references indexed in Scilit:
- Inhibitory Effect of Depolymerized Sulfated Galactans from Marine Red Algae on the Growth and Adhesion of Diarrheagenic Escherichia coliMarine Drugs, 2019
- DIARRHEA: A CORRECT ALGORITHM OF DOCTOR’S ACTIONSMedical Council, 2017
- ACUTE DIARRHEA OF BACTERIAL ETIOLOGY: DIFFERENTIAL DIAGNOSIS AND TREATMENTMedical Council, 2016
- Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013The Lancet, 2015
- Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013The Lancet, 2014
- Gastro 2013 APDW/WCOG Shanghai Working Party Report: Chronic diarrhea: Definition, classification, diagnosisJournal of Gastroenterology and Hepatology, 2013
- Global Causes of Diarrheal Disease Mortality in Children <5 Years of Age: A Systematic ReviewPLOS ONE, 2013
- Bioactive compounds in seaweed: functional food applications and legislationJournal of Applied Phycology, 2011
- Mechanisms of infectious diarrheaNature Clinical Practice Gastroenterology & Hepatology, 2008
- Diarrhoea: a significant worldwide problemInternational Journal of Antimicrobial Agents, 2000