Pediatric double positive anti‐glomerular basement membrane antibody and anti‐neutrophil cytoplasmic antibody glomerulonephritis—A case report with review of literature
- 25 February 2021
- journal article
- review article
- Published by Wiley in Journal of Clinical Apheresis
- Vol. 36 (3), 505-510
- https://doi.org/10.1002/jca.21886
Abstract
Anti‐glomerular basement membrane (GBM) disease is a rarely described entity in the pediatric population, especially in those less than 3 years old. Even rarer, is double seropositive disease, consisting of anti‐GBM antibody plus anti‐neutrophil cytoplasmic antibodies. Both single and double antibody positive diseases are characterized by rapidly progressive glomerulonephritis, often without pulmonary involvement in the pediatric population. We report the case of a 2‐year‐old child with double seropositive anti‐GBM disease, the youngest in the current literature, along with the role of therapeutic plasma exchange and rituximab in disease treatment.Keywords
This publication has 20 references indexed in Scilit:
- Coexistence of Anti-Glomerular Basement Membrane Antibodies and Anti-Neutrophil Cytoplasmic Antibodies in a Child With Human Leukocyte Antigen Susceptibility and Detailed Antibody DescriptionMedicine, 2015
- Goodpasture's disease: A report of ten cases and a review of the literatureAutoimmunity Reviews, 2013
- Pulmonary renal syndrome in a child with coexistence of anti-neutrophil cytoplasmic antibodies and anti-glomerular basement membrane disease: case report and literature reviewBMC Nephrology, 2013
- A 25-year experience with pediatric anti-glomerular basement membrane diseasePediatric Nephrology, 2010
- Rescue of renal function in a 3-year-old girl with Goodpasture's syndrome with a brief review of literatureClinical Kidney Journal, 2010
- Anti-GBM antibodies co-exist with MPO–ANCA in a 4-year-old girl with acute renal failurePediatric Nephrology, 2009
- Coexistence of Anti-Glomerular Basement Membrane Antibodies and Myeloperoxidase-ANCAs in Crescentic GlomerulonephritisAmerican Journal of Kidney Diseases, 2005
- Anti-GBM and anti-MPO antibodies coexist in a case of pulmonary renal syndromePediatric Nephrology, 2005
- Plasma exchange: Why we do what we doJournal of Clinical Apheresis, 2002
- A 12-year-old girl with pulmonary hemorrhage, skin lesions, and hematuriaAmerican Journal of Kidney Diseases, 1999