Mild and Chemoselective Phosphorylation of Alcohols Using a Ψ-Reagent
- 9 September 2021
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 23 (24), 9337-9342
- https://doi.org/10.1021/acs.orglett.1c02736
Abstract
An operationally simple, scalable, and chemoselective method for the direct phosphorylation of alcohols using a P(V)-approach based on the Psi-reagent platform is disclosed. The method features a broad substrate scope of utility in both simple and complex settings and provides access to valuable phosphorylated alcohols that would be otherwise difficult to obtain.Keywords
Funding Information
- Narodowa Agencja Wymiany Akademickiej (PPN/BEK/2020/1/00111/DEC/1)
- â??la Caixaâ? Foundation (ID 100010434 LCF/BQ/PR20/11770014)
- H2020 Marie SkÅ?odowska-Curie Actions (H2020-MSCA-IF-2016-GF-749359-EnanSET)
- National Institute of General Medical Sciences (118176)
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