We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of EF-hand calcium binding domain 4A, encoded by EFCAB4A when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, EFCAB4A expression was correlated with recurrence-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. EFCAB4A may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.