ATG8ylation of proteins: A way to cope with cell stress?
Open Access
- 20 October 2021
- journal article
- editorial
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 220 (11)
- https://doi.org/10.1083/jcb.202108120
Abstract
The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.Keywords
Funding Information
- Lysosomal Health in Ageing
- South Australian Health and Medical Research Institute
- Australian National Health and Medical Research Council (GNT1106471, GNT1160315, GNT1144500)
- Australian National Health and Medical Research Council (GNT1103006)
- Australian Research Council (FT1601100063)
- ARC (DP200100347)
- ARC (DP210100665)
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