Successful use of IFN-γ for refractory systemic infection with Candida tropicalis in a child with AML and CARD9 mutation
Published: 30 June 2022
Archives of Pathology and Clinical Research , Volume 6, pp 013-015; https://doi.org/10.29328/journal.apcr.1001031
Abstract: Infectious complications remain major causes of treatment-related morbidity and mortality in children with acute myelogenous leukemia (AML) due to the intensive chemotherapeutic regimens needed to treat this disease. Invasive fungal infections (IFI) represent a particularly severe condition that affects 5% - 13% of AML patients with a persistently unacceptable mortality rate of 40%.
Keywords: children / treatment / AML / chemotherapeutic / Invasive / unacceptable / refractory / systemic / fungal
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