A case of secondary syphilis presenting as optic neuritis
- 25 February 2010
- journal article
- case report
- Published by Springer Science and Business Media LLC in Neurological Sciences
- Vol. 31 (3), 365-367
- https://doi.org/10.1007/s10072-010-0222-8
Abstract
Neurosyphilis is still a significant medical problem in developing countries and syphilitic ocular manifestations are often not diagnosed due to the lack of typical characteristics. We describe the case of a 59-year-old homosexual man with a 1-month history of decreased vision acuity in his left eye who was diagnosed with neurosyphilis and received treatment with intravenous penicillin G (16 million units in divided daily doses), with great improvement of visual acuity and CSF examination findings. The interest of this case is not only represented by the unusually early ocular involvement, but also by the rapid evolution of the disease into the secondary stage in a man who had had one at-risk homosexual relationship only 3 months before the onset symptoms. We also support the view that the presence of ocular involvement in syphilitic patients is suggestive of involvement of the CNS and should be considered synonymous with neurosyphilis.Keywords
This publication has 10 references indexed in Scilit:
- Ocular syphilis – indicator of previously unknown HIV-infectionJournal of Infection, 2009
- Secondary Syphilis with Ocular Manifestations in Older AdultsClinical Infectious Diseases, 2008
- Manifestations and Treatment of Ocular Syphilis During an Epidemic in FranceSexually Transmitted Diseases, 2007
- Clinical and magnetic resonance imaging findings of HIV-Negative patients with neurosyphilisZeitschrift für Neurologie, 2007
- Syphilis: Reemergence of an Old AdversaryOphthalmology, 2006
- Neurosyphilis with optic neuritis: an updatePublished by Oxford University Press (OUP) ,2006
- Syphilis and HIV: a dangerous combinationThe Lancet Infectious Diseases, 2004
- Neurosyphilis presenting with optic neuropathyAnnals of Ophthalmology, 2000
- Syphilis: Review with Emphasis on Clinical, Epidemiologic, and Some Biologic FeaturesClinical Microbiology Reviews, 1999
- Invasion of the Central Nervous System by Treponema pallidum: Implications for Diagnosis and TreatmentAnnals of Internal Medicine, 1988