Dengue: A Minireview
Top Cited Papers
Open Access
- 30 July 2020
- Vol. 12 (8), 829
- https://doi.org/10.3390/v12080829
Abstract
Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments.Keywords
This publication has 274 references indexed in Scilit:
- Worldwide Spread of Dengue Virus Type 1PLOS ONE, 2013
- Analysis of Effects of Meteorological Factors on Dengue Incidence in Sri Lanka Using Time Series DataPLOS ONE, 2013
- Structural insights into the neutralization mechanism of a higher primate antibody against dengue virusThe EMBO Journal, 2011
- Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1Nature Genetics, 2011
- Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexesThe Lancet Infectious Diseases, 2010
- Molecular evolution of dengue viruses: Contributions of phylogenetics to understanding the history and epidemiology of the preeminent arboviral diseaseInfection, Genetics and Evolution, 2009
- Structural proteomics of dengue virusCurrent Opinion in Microbiology, 2008
- DengueThe Lancet, 2007
- Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever‐dengue shock syndrome (DHF/DSS)Immunology & Cell Biology, 2006
- Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic feverNature Medicine, 2003