Distinct Group B Streptococcus Sequence and Capsule Types Differentially Impact Macrophage Stress and Inflammatory Signaling Responses
Open Access
- 16 April 2021
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 89 (5)
- https://doi.org/10.1128/iai.00647-20
Abstract
Group B Streptococcus (GBS) is an opportunistic bacterial pathogen that can contribute to the induction of preterm birth in colonized pregnant women and to severe neonatal disease. Many questions regarding the mechanisms that drive GBS-associated pathogenesis remain unanswered, and it is not yet clear why virulence has been observed to vary so extensively across GBS strains.Keywords
Funding Information
- HHS | National Institutes of Health (AI134036, HD090061)
- HHS | National Institutes of Health (AI154192)
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