Self-assembling peptide scaffolds in the clinic
Open Access
- 17 February 2021
- journal article
- research article
- Published by Springer Science and Business Media LLC in npj Regenerative Medicine
- Vol. 6 (1), 1-8
- https://doi.org/10.1038/s41536-020-00116-w
Abstract
Well-defined scaffold hydrogels made of self-assembling peptides have found their way into clinical products. By examining the properties and applications of two self-assembling peptides—EAK16 and RADA16—we highlight the potential for translating designer biological scaffolds into commercial products.Keywords
This publication has 50 references indexed in Scilit:
- Controlling the movement of moleculesQuarterly Reviews of Biophysics, 2019
- Synthetic TissuesMolecular Frontiers Journal, 2017
- Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent miceNature Medicine, 2016
- Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primatesNature Biotechnology, 2016
- Designing materials for biology and medicineNature, 2004
- Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffoldsProceedings of the National Academy of Sciences of the United States of America, 2000
- Self-complementary oligopeptide matrices support mammalian cell attachmentBiomaterials, 1995
- Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane.Proceedings of the National Academy of Sciences of the United States of America, 1993
- Configurations of Polypeptide Chains With Favored Orientations Around Single BondsProceedings of the National Academy of Sciences of the United States of America, 1951
- The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chainProceedings of the National Academy of Sciences of the United States of America, 1951