Application of Insertable Cardiac Monitor in Establishing a Dog Model of Atrial Fibrillation by High-Frequency Right Atrial Pacing
- 1 May 2020
- journal article
- research article
- Published by International Scientific Information, Inc. in Medical Science Monitor
- Vol. 26, e920071-e920071-11
- https://doi.org/10.12659/MSM.920071
Abstract
Background: On the base of traditional modeling with high-frequency atrial pacing, insertable cardiac monitor is innovatively used to track the incidence of atrial fibrillation (AF), to observe the efficiency and safety of establishment in AF model. Material/Methods: Twelve adult beagle dogs were randomly divided into a blank control group and an AF model group. The thin- nest available bipolar solid electrode lead-3830 was implanted in AF group, connected to AF pacemaker to establish a high-frequency atrial pacing model by AOO pacing mode, and the occurrence of AF was tracked in real time by an insertable cardiac monitor Reveal LINQ. The areas of the left and the right atrium were measured by echocardiography. In addition, the morphology of left atrial tissues was observed using light and electron microscopes. Results: The insertable cardiac monitor Reveal LINQ sensitively, conveniently, accurately, efficiently, and dynamically re- corded the AF load in AF group. After the successfully establishment of the AF mode, the area of the left atrium and right atrium were significantly enlarged compared with that before modeling by echocardiography. Furthermore, the area of the left atrium and right atrium in the AF group were larger than that in the control group. The morphological observation of the left atrium tissues in both groups prompted the reconstruction of the atrial structure in dogs in the AF group. Conclusions: The application of insertable cardiac monitor Reveal LINQ improves the efficiency of monitoring the AF load, with high sensitivity, convenience, and accuracy.This publication has 19 references indexed in Scilit:
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