Threatened Ayurvedic Herb (Seeta Ashoka) Substitution Options for Menorrhagia-based on Bioactive Principle’s Molecular Docking Study
Open Access
- 28 July 2022
- journal article
- review article
- Published by EManuscript Technologies in International Journal of Pharmaceutical Investigation
- Vol. 12 (3), 250-254
- https://doi.org/10.5530/ijpi.2022.3.45
Abstract
Molecular docking studies are used to identify cultivated/ abundant herbs such as Coriander, Burmuda grass or Asparagus as potential replacement for Seeta Ashoka- Saraca asoca (Roxb.) De Wilde, syn. S. indica Linn. a rare Indian medicinal forest plant, threatened with extinction due to over harvest. Its bark is used to make the famous Ayurvedic medicine “Ashokarishta” to treat menorrhagia and as a uterine tonic like ergot but is mostly adulterated. We tested using molecular docking studies Quercetin and other polyphenols from Coriander as potent anti-inflammatory ingredients, similar to NSAID (Non-steroidal anti-inflammatory drugs)., Polyalthia longifolia, the common adulterant is also be noted to be effective as its bark contains 30-50% of tannin than Saraca asoca, so may help in thrombosis.Keywords
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