The Role of Laparoscopic Surgery in Localized Pancreatic Neuroendocrine Tumours
- 27 February 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Current Treatment Options in Oncology
- Vol. 22 (4), 1-9
- https://doi.org/10.1007/s11864-021-00824-5
Abstract
Opinion statement Pancreatic neuroendocrine tumours (PNETs) are a rare and heterogeneous group of tumours with various clinical manifestations and biological behaviours. They represent approximately 2–4% of all pancreatic tumours, with an incidence of 2–3 cases per million people. PNETs are classified clinically as non-functional or functional, and pancreatic resection is recommended for lesions greater than 2 cm. The surgical approach can involve “typical” and “atypical” resections depending on the number, size and location of the tumour. Typical resections include pancreaticoduodenectomy, distal pancreatectomy enucleation and, rarely, total pancreatectomy. Atypical resections comprise central pancreatectomies or enucleations. Minimally invasive pancreatic resection has been proven to be technically feasible and safe in high-volume and specialized centres with highly skilled laparoscopic surgeons, with consolidated benefits for patients in the postoperative course. However, open and minimally invasive pancreatic surgery remains to have a high rate of complications; there is no specific technical contraindication to minimally invasive pancreatic surgery, but an appropriate patient selection is crucial to obtain satisfactory clinical and oncological outcomes.Keywords
This publication has 26 references indexed in Scilit:
- Reappraisal of post-pancreatectomy hemorrhage (PPH) classifications: do we need to redefine grades A and B?HPB, 2018
- Surgical resection of neuroendocrine tumors of the pancreas (pNETs) by minimally invasive surgery: the laparoscopic approachGland Surgery, 2018
- Laparoscopic management of neuroendocrine tumors: state-of-the-artTranslational Gastroenterology and Hepatology, 2017
- Is there any role for minimally invasive surgery in NET?Reviews in Endocrine and Metabolic Disorders, 2017
- Pancreatoduodenectomy (PD) and postoperative pancreatic fistula (POPF)Medicine, 2017
- Minimally invasive distal pancreatectomy for PNETs: laparoscopic or robotic approach?Oncotarget, 2017
- Short- and long-term outcomes of laparoscopic organ-sparing resection in pancreatic neuroendocrine tumors: a single-center experienceSurgical Endoscopy, 2017
- Systematic review and meta-analysis on laparoscopic pancreatic resections for neuroendocrine neoplasms (PNENs)Expert Review of Gastroenterology & Hepatology, 2016
- Indications and contraindications for laparoscopic pancreas surgeryPublished by Wiley ,2016
- Pancreatic Neuroendocrine Tumors: an UpdateIndian Journal of Surgery, 2015