Fatigue, Sleepiness, Anxiety-Depression Score, Calories And BDNF Serum Level, Quality Of Life Alteration During Holy Ramadhan Month

Abstract

Introduction: Ramadhan fasting increases mental and physical health. The study aims to evaluate the effect of Ramadhan fasting on fatigue, sleepiness, depression and anxiety mood, quality of life (QoL), and Brain-derived neurotrophic factor (BDNF) serum level. Methods: Twenty participants are included in the fasting group (FG), and nineteen participants are included in the non-fasting group (NFG). Fatigue severity scales (FSS), fatigue VAS, Epworth sleepiness scale (ESS), hospital depression and anxiety score (HADS), Beck depression inventory (BDI)-II, Short form 12 (SF-12), and BDNF in both groups were assessed at five-time points: one week before Ramadhan (T1), in the middle of Ramadhan (T2), the last days of Ramadhan (T3), one week after Ramadhan fasting (T4) two weeks after Ramadhan (T5). Results: We found no significant differences across the time points between FG and NFG groups in all variables (p>0.05). There is a significant correlation between fatigue VAS with BDNF serum levels (r > r table), SF-12 PCS (r>r table) with BDNF, SF-12 MCS (r>r table). There is no correlation between fatigue, depression and anxiety intensity, sleepiness, QoL, BDI-II, and BDNF serum levels with calories, BDI-II, and BDNF of fasting group in Ramadhan (r < r table). Conclusions: Ramadhan fasting has positive effects on fatigue and mood. Ramadhan fasting does not have a significant effect on sleepiness, physical exercise, and calories consumed. Fatigue VAS and SF-12 PCS can replace the serum BDNF. Pendahuluan: Puasa Ramadhan meningkatkan kesehatan mental dan fisik. Penelitian ini bertujuan untuk mengevaluasi pengaruh puasa Ramadhan terhadap kelelahan, rasa kantuk, mood depresi dan kecemasan, kualitas hidup, dan tingkat serum Brain-derived neurotrophic factor (BDNF) Metode: Dua puluh peserta termasuk dalam kelompok puasa dan sembilan belas peserta termasuk dalam kelompok tidak puasa. Kedua kelompok dinilai Fatigue severity scales (FSS), fatigue VAS, Epworth sleepiness scale (ESS), hospital depression and anxiety score (HADS), Beck depression inventory (BDI)-II, Short form 12 (SF-12), dan BDNF pada lima waktu: satu minggu sebelum Ramadhan (T1), di tengah Ramadhan (T2), hari terakhir Ramadhan (T3), satu minggu setelah puasa Ramadhan (T4), dan dua minggu setelah Ramadhan (T5). Hasil: Tidak ditemukan perbedaan yang signifikan antara kelompok puasa dan tidak puasa di semua variabel (p>0,05). Ada hubungan yang signifikan antara fatigue VAS dengan kadar serum BDNF (r > r tabel), SF-12 PCS (r>r tabel) dengan BDNF, SF-12 MCS (r>r tabel). Tidak ada hubungan antara fatigue, depresi dan kecemasan, rasa kantuk, kualitas hidup, BDI-II, dan kadar BDNF serum dengan kalori, BDI-II, dan BDNF pada kelompok puasa (r < r tabel). Kesimpulan: Puasa Ramadhan mempunyai efek positif pada fatigue dan mood. Puasa Ramadhan tidak mempunyai efek yag signifikan terhadap rasa kantuk, latihan fisik, dan kalori yang dikonsumsi. Fatigue VAS dan SF-12 PCS dapat digunakan untuk mengganti serum BDNF.