The present study refers to an origami workshop of visual arts activities and interdisciplinary research, implemented during COVID-19 pandemics in online distance education in Higher Education. The aim of the workshop was to engage pre-service preschool teachers in origami activities which should then be used and implemented in activities mainly in early childhood and primary education. The paper presents: a. the structure and the content of the workshop with activities by hand and in digital form, and b. the students’ responses regarding their experience and perceptions about origami based on quantitative data. The results revealed that the interplay of physical and digital art and space composed an inter-media origami experience with various potential implementations in education.