Monitoring response in lymphomas: qualitative, quantitative, or what else?
- 22 July 2018
- journal article
- review article
- Published by Taylor & Francis Ltd in Leukemia & Lymphoma
- Vol. 60 (2), 302-308
- https://doi.org/10.1080/10428194.2018.1480773
Abstract
The Deauville criteria (DC) shall always be used to report interim and final PET and to assign metabolic response categories in FDG-avid lymphoma. A recent review article supports the role of quantitative extension of the DC to improve response assessment in lymphoma. We analyze different quantitative approach, to help physician to better distinguish what has to be done in every day clinical practice respect to what represent interesting insights and ongoing research. Respect to DC, all the proposed quantitative approaches obtained in retrospective studies, requires mature follow-up and a validation in independent cohorts of lymphoma patients. Moreover, the sensitivity of the system, not the adequate specificity of the tracer and the biology of the disease together with the DC, influence the accuracy of PET/CT. In conclusions, in current clinical practice, the DC, validated in a large cohort of lymphoma patients, represent the standard criteria for PET interpretation.This publication has 25 references indexed in Scilit:
- Impact of Different Standardized Uptake Value Measures on PET-Based Quantification of Treatment ResponseJournal of Nuclear Medicine, 2013
- An international confirmatory study of the prognostic value of early PET/CT in diffuse large B-cell lymphoma: comparison between Deauville criteria and ΔSUVmaxEuropean Journal of Nuclear Medicine and Molecular Imaging, 2013
- International Validation Study for Interim PET in ABVD-Treated, Advanced-Stage Hodgkin Lymphoma: Interpretation Criteria and Concordance Rate Among ReviewersJournal of Nuclear Medicine, 2013
- SUVmax reduction improves early prognosis value of interim positron emission tomography scans in diffuse large B-cell lymphomaBlood, 2011
- Repeatability of 18F-FDG PET in a Multicenter Phase I Study of Patients with Advanced Gastrointestinal MalignanciesJournal of Nuclear Medicine, 2009
- Prognostic Value of Interim 18F-FDG PET in Patients with Diffuse Large B-Cell Lymphoma: SUV-Based Assessment at 4 Cycles of ChemotherapyJournal of Nuclear Medicine, 2009
- Report on the First International Workshop on interim-PET scan in lymphomaLeukemia & Lymphoma, 2009
- Guidelines for 18F-FDG PET and PET-CT imaging in paediatric oncologyEuropean Journal of Nuclear Medicine and Molecular Imaging, 2008
- Early 18F-FDG PET for Prediction of Prognosis in Patients with Diffuse Large B-Cell Lymphoma: SUV-Based Assessment Versus Visual AnalysisJournal of Nuclear Medicine, 2007
- Early Interim 2-[18F]Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography Is Prognostically Superior to International Prognostic Score in Advanced-Stage Hodgkin's Lymphoma: A Report From a Joint Italian-Danish StudyJournal of Clinical Oncology, 2007