The Imiquimod Induced Psoriatic Animal “Model: Scientific Implications

Abstract

Imiquimod (IMQ), hallmark ligand of Toll-like Receptor (TLR)-7 in mouse and TLR7/8 in human has been known to be protective against human papilloma virus-caused warts, actinic keratosis and basal cell carcinomas. Due to its small chemical structure and lipophilicity, it is really suitable for topical administration, thus successfully used as an ointment for the aforementioned diseases [1,2].