Chemotherapy against bladder cancer in geriatric patients.

Abstract

The number of geriatric bladder cancer patients is now increasing in spite of little is known regarding the safety and efficacy of standard treatment for the patients due to luck of data in geriatric patients. Although they should be treated by modified standard treatment adjusted for their deteriorated physical activity, such treatment regimens are not established. Bladder preservation therapy could be recommended for geriatric patients with invasive bladder can- cer, which shows comparable survival benefit with radical cystectomy. Although chemother- apy could be a treatment option for geriatric patients, geriatric assessment before treatment is recommended to choose appropriate candidates to modify therapeutic regimens. Standard treatment for geriatric patients with cancer would be established based on clinical trials in- volving geriatric assessment.