Gene reuse facilitates rapid radiation and independent adaptation to diverse habitats in the Asian honeybee
Open Access
- 1 December 2020
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Advances
- Vol. 6 (51), eabd3590
- https://doi.org/10.1126/sciadv.abd3590
Abstract
Animals with recent shared ancestry frequently adapt in parallel to new but similar habitats, a process often underlined by repeated selection of the same genes. Yet, in contrast, few examples have demonstrated the significance of gene reuse in colonization of multiple disparate habitats. By analyzing 343 genomes of the widespread Asian honeybee, Apis cerana, we showed that multiple peripheral subspecies radiated from a central ancestral population and adapted independently to diverse habitats. We found strong evidence of gene reuse in the Leucokinin receptor (Lkr), which was repeatedly selected in almost all peripheral subspecies. Differential expression and RNA interference knockdown revealed the role of Lkr in influencing foraging labor division, suggesting that Lkr facilitates collective tendency for pollen/nectar collection as an adaptation to floral changes. Our results suggest that honeybees may accommodate diverse floral shifts during rapid radiation through fine-tuning individual foraging tendency, a seemingly complex process accomplished by gene reuse.Funding Information
- National Natural Science Foundation of China (31772493)
- National Science Foundation of China (31470123)
- Program of Ministry of Science and Technology of China (2018FY100403)
- National Special Support Program for High-level Talents
- Jilin Science and Technology Program (20030561)
- National Mission on Himalayan Studies (NMHS)-Almora, Ministry of Environment, Forest and Climate Change, Government of India (GBPNI/NMHS-2017-18/MG-12)
- Beijing Advanced Innovation Center for Food Nutrition and Human Health through China Agricultural University
This publication has 58 references indexed in Scilit:
- Molecular evolution of peptidergic signaling systems in bilateriansProceedings of the National Academy of Sciences of the United States of America, 2013
- Floral humidity as a reliable sensory cue for profitability assessment by nectar-foraging hawkmothsProceedings of the National Academy of Sciences of the United States of America, 2012
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene ClustersOMICS: A Journal of Integrative Biology, 2012
- The genomic basis of adaptive evolution in threespine sticklebacksNature, 2012
- Robust relationship inference in genome-wide association studiesBioinformatics, 2010
- Global pollinator declines: trends, impacts and driversTrends in Ecology & Evolution, 2010
- The Leucokinin Pathway and Its Neurons Regulate Meal Size in DrosophilaCurrent Biology, 2010
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataBioinformatics, 2009
- Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype ClusteringAmerican Journal of Human Genetics, 2007
- The evolutionary significance of cis-regulatory mutationsNature Reviews Genetics, 2007