Synthesis and reactions of 3-aminotetrachloroquinazolin-2,4-dione
Open Access
- 31 December 2011
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 2 (4), 514-518
- https://doi.org/10.5155/eurjchem.2.4.514-518.479
Abstract
N-phenylsulphonyloxytetrachlorophthalimide was obtained by treatment of N-hydroxy tetrachlorophthalimide with benzenesulphonyl chloride. Also, the titled compound 3 was obtained by reaction of compound 2 with hydrazine hydrate via Lossen rearrangement. Compound 3 used as starting material for the synthesis of new pyrimidine and quinazolinedione derivatives containing four chlorine atoms which have pharmacological activity.Keywords
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