Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms
Open Access
- 18 July 2020
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 72 (8), 1444-1447
- https://doi.org/10.1093/cid/ciaa948
Abstract
Fecal microbiota transplantation (FMT) yields variable intestinal decolonization results for multidrug-resistant organisms (MDROs). This study showed significant reductions in antibiotic duration, bacteremia, and length of stay in 20 patients colonized/infected with MDRO receiving FMT (compared with pre-FMT history, and a matched group not receiving FMT), despite modest decolonization rates.Keywords
Funding Information
- National Institute for Health Research
- Imperial Biomedical Research Centre
- Medical Research Council
- Wellcome Trust
- Medical Research Council (MR/R000875/1)
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