Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia
- 1 February 2021
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 93 (11), 6393-6397
- https://doi.org/10.1002/jmv.26815
Abstract
We assessed maternal and infant cytomegalovirus (CMV) infection in Colombia. Maternal serum was tested for CMV immunoglobulin G antibodies at a median of 10 (interquartile range: 8–12) weeks gestation (n = 1501). CMV DNA polymerase chain reaction was performed on infant urine to diagnose congenital (≤21 days of life) and postnatal (>21 days) infection. Maternal CMV seroprevalence was 98.1% (95% confidence interval [CI]: 97.5%–98.8%). Congenital CMV prevalence was 8.4 (95% CI: 3.9%–18.3%; 6/711) per 1000 live births. Among 472 infants without confirmed congenital CMV infection subsequently tested at age 6 months, 258 (54.7%, 95% CI: 50.2%–59.1%) had postnatal infection.Funding Information
- United States Agency for International Development
- Centers for Disease Control and Prevention
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