Probabilistic characterisation of deep brain stimulation in patients with tardive syndromes

Abstract
Group-level neuroimaging analyses can demonstrate optimal stimulation areas, tracts and functional networks associated with maximal clinical benefits during DBS. To our knowledge, this approach has not yet been applied to TS. The objectives of this study were to (1) retrospectively examine clinical outcomes from seven patients with TS GPi-DBS and (2) use neuroimaging analysis to investigate brain circuits possibly related to efficacy.