The Prevalence of Barrett’s Esophagus Among a Saudi Arabian Population
- 4 August 2020
- journal article
- research article
- Published by Springer Science and Business Media LLC in Digestive Diseases and Sciences
- Vol. 66 (7), 2311-2316
- https://doi.org/10.1007/s10620-020-06503-z
Abstract
Background While gastroesophageal reflux disease (GERD) is common in Middle Eastern countries, little data exists on the epidemiology of Barrett’s esophagus (BE). Aims We aimed to determine the prevalence of BE among patients undergoing esophagogastroduodenoscopy (EGD) in a cohort of Saudi patients. Methods We retrospectively reviewed the endoscopy database at an academic tertiary care center. Consecutive adult patients who underwent an EGD for any indication between May 2014 and December 2018 were included. The prevalence of both endoscopically and histologically reported BE was determined. Multivariate regression analysis was used to identify factors associated with BE. Results A total of 2805 patients were included. The mean age was 48 years (± 18.6) and 38.7% were male patients. BE was reported endoscopically in 18 (0.64%) and confirmed histologically in 9 patients (0.32%). Among patients with endoscopically reported BE, the mean age was 50.3 (± 16.1) years and 13 (72.2%) were male patients. Of patients with BE, short-segment BE was reported in 14 (77.8%) patients. Among the 9 patients with histologically confirmed BE; only one patient had dysplastic BE. On univariate analysis, BE was associated with male gender (p < 0.01), but not with age > 50, hiatal hernia, obesity or EGD performed for GERD related indications. On multivariate regression analysis, male gender was the only factor associated with BE (aOR 3.77, 95% CI 1.39–11.97, p = 0.01). Conclusion BE was endoscopically reported in 0.64% and histologically confirmed in 0.32% of this cohort of Saudi patients. Male gender was the only factor associated with BE.Keywords
This publication has 23 references indexed in Scilit:
- Prevalence of symptoms of gastroesopahgeal reflux in a cohort of Saudi Arabians: A study of 1265 subjectsSaudi Journal of Gastroenterology, 2014
- British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagusGut, 2013
- Cigarette smoking and the risk of Barrett's esophagus: A systematic review and meta‐analysisJournal of Gastroenterology and Hepatology, 2013
- Update on the epidemiology of gastro-oesophageal reflux disease: a systematic reviewGut, 2013
- Meta-Analyses of the Effect of Symptoms of Gastroesophageal Reflux on the Risk of Barrett's EsophagusThe American Journal of Gastroenterology, 2010
- Age- and sex-specific yield of Barrett's esophagus by endoscopy indicationGastrointestinal Endoscopy, 2010
- Barrett's esophagus and endoscopically assessed esophagogastric junction integrity in 1000 consecutive Turkish patients undergoing endoscopy: a prospective studyDiseases of the Esophagus, 2009
- Prevalence of Barrett’s Esophagus in the General Population: An Endoscopic StudyGastroenterology, 2005
- A Systematic Review and Meta-Analysis of the Sex Ratio for Barrett's Esophagus, Erosive Reflux Disease, and Nonerosive Reflux DiseaseAmerican Journal of Epidemiology, 2005
- Screening for Barrett’s esophagus in colonoscopy patients with and without heartburnGastroenterology, 2003