Subjective Cognitive Decline and Related Cognitive Deficits
Open Access
- 19 May 2020
- journal article
- review article
- Published by Frontiers Media SA in Frontiers in Neurology
- Vol. 11, 247
- https://doi.org/10.3389/fneur.2020.00247
Abstract
Since late stage dementia, including Alzheimer's disease (AD), cannot be reversed by any available drugs, there is increasing research interest in the preclinical stage of AD, i.e., subjective cognitive decline (SCD). SCD is characterized by self-perceptive cognitive decline but is difficult to detect using objective tests. At SCD stage, the cognitive deficits can be more easily reversed compared to that of mild cognitive impairment (MCI) and AD only if accurate diagnosis of SCD and early intervention can be developed. In this paper, we review the recent progress of SCD research including current assessment tools, biomarkers, neuroimaging, intervention and expected prognosis, and the potential relevance to traumatic brain injury (TBI)-induced cognitive deficits.Funding Information
- National Natural Science Foundation of China
- Beijing Municipal Science and Technology Commission
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