Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial
- 20 April 2020
- journal article
- research article
- Published by Springer Science and Business Media LLC in AIDS and Behavior
- Vol. 24 (11), 3164-3175
- https://doi.org/10.1007/s10461-020-02875-5
Abstract
We tested an intervention that aimed to increase retention in antiretroviral therapy (ART) among HIV-positive pregnant and postpartum women, a population shown to be vulnerable to poor ART outcomes. 133 pregnant women initiating ART at 2 hospitals in Uganda used real time-enabled wireless pill monitors (WPM) for 1 month, and were then randomized to receive text message reminders (triggered by late dose-taking) and data-informed counseling through 3 months postpartum or standard care. We assessed “full retention” (proportion attending all monthly clinic visits and delivering at a study facility; “visit retention” (proportion of clinic visits attended); and “postpartum retention” (proportion retained at 3 months postpartum). Intention-to-treat and per protocol analyses found that retention was relatively low and similar between groups, with no significant differences. Retention declined significantly post-delivery. The intervention was unsuccessful in this population, which experiences suboptimal ART retention and is in urgent need of effective interventions.Keywords
Funding Information
- National Institute of Mental Health (1R34MN103075)
This publication has 55 references indexed in Scilit:
- Association between Male Partner Involvement and the Uptake of Prevention of Mother-to-Child Transmission of HIV (PMTCT) Interventions in Mwanza District, Malawi: A Retrospective Cohort StudyPLOS ONE, 2013
- The effect of weekly short message service communication on patient retention in care in the first year after HIV diagnosis: study protocol for a randomised controlled trial (WelTel Retain)BMJ Open, 2013
- Male involvement in prevention programs of mother to child transmission of HIV: a systematic review to identify barriers and facilitatorsSystematic Reviews, 2013
- Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in ChinaAIDS Research and Treatment, 2013
- Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: a randomized controlled trial of text message remindersAIDS, 2011
- Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trialThe Lancet, 2010
- Exploring the Patterns of Use and the Feasibility of Using Cellular Phones for Clinic Appointment Reminders and Adherence Messages in an Antiretroviral Treatment Clinic, Durban, South AfricaAIDS Patient Care and STDs, 2010
- Retention in Care among HIV-Infected Patients in Resource-Limited Settings: Emerging Insights and New DirectionsCurrent HIV/AIDS Reports, 2010
- Real-Time Adherence Monitoring for HIV Antiretroviral TherapyAIDS and Behavior, 2010
- Patient retention in antiretroviral therapy programs up to three years on treatment in sub‐Saharan Africa, 2007–2009: systematic reviewTropical Medicine & International Health, 2010