MicroRNAs as non-invasive biomarkers of renal disease

Abstract
With an estimated global prevalence of chronic kidney disease (CKD) of 11–13%, non-invasive biomarkers of renal pathology are desperately required to enhance early diagnosis, guide prognosis and monitor response to treatment [ 1]. Currently, the mainstay of renal functional monitoring remains measurement of blood urea, serum creatinine and urinalysis, with renal biopsies adopted when diagnostic clarity is required.
Funding Information
  • Medical Research Council (MR/S001743/1)
  • Kidney Research UK (SF_001_20181122;RP_042_20160304)