Detection of the Viral Infectious Diseases in Blood by Surface-Enhanced Raman Spectroscopy: Mini Review

Abstract

Blood is the most complex fluid in the body. Blood contains a large number and variety of cells and molecules. When viruses infect a host, biomarkers of the viral infections are rare. Thus, it is hard to detect in blood. Recently, Surface Enhanced Raman Spectroscopy (SERS) has been shown to be promising in infectious disease detection. SERS provides a sensitive, rapid, and non-invasive approach to virus detection. Several studies have demonstrated the use of SERS in detecting various types of infectious diseases. In this report, we briefly review recent advances in the detection of infectious diseases by using SERS.