Rituximab vs Low-Dose Mycophenolate Mofetil in Recurrence of Steroid-Dependent Nephrotic Syndrome in Children and Young Adults

Abstract

Children and young adults with steroid-dependent nephrotic syndrome (SDNS) are exposed to the toxic effects of both steroids and common steroid-sparing agents, such as calcineurin inhibitors, reporting an increased risk of kidney failure.¹ Alternative low-toxicity, long-acting therapies are needed to treat SDNS.¹ Identify all potential conflicts of interest that might be relevant to your comment. Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. Err on the side of full disclosure. If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response. Not all submitted comments are published. Please see our commenting policy for details.