Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production
Open Access
- 1 November 2020
- journal article
- research article
- Published by Taylor & Francis Ltd in Mycobiology
- Vol. 48 (6), 512-517
- https://doi.org/10.1080/12298093.2020.1831135
Abstract
Cordyceps militaris has been reported to the diverse pharmaceutical effects including cancer, inflammatory diseases, and bacteria or virus infection. However, the effect of C. militaris on exercise performance has not yet been elucidated. In this study, we investigated the beneficial effect of C. militaris on exercise performance. To evaluate exercise performance, we prepared C. militaris ethyl acetate extract (CMEE) and conducted grip strength tests every week after administration. Additionally, blood samples were collected at the end of the experiment for biochemical analysis. The administration of CMEE slightly increased grip strength, and this result was similar to the red ginseng treated group. According to the result of biochemical analysis, CMEE had an effect on the biomarkers related to ATP generation pathway but had little influence on the muscle fatigue related biomarkers. Therefore, C. militaris has the possibility of improving exercise performance, which could be associated with the increase in ATP production rather than the decrease in muscle fatigue during exercise.Funding Information
- Bio-industry Technology Development Program (316025-05)
- National Research Foundation (NRF) Grant funded by the Korea government (2019R1A2C2005157)
This publication has 26 references indexed in Scilit:
- Effect of Curcumin Supplementation on Physiological Fatigue and Physical Performance in MiceNutrients, 2015
- Studies on the Antifatigue Activities ofCordyceps militarisFruit Body Extract in Mouse ModelEvidence-Based Complementary and Alternative Medicine, 2015
- Exercise, GLUT4, and Skeletal Muscle Glucose UptakePhysiological Reviews, 2013
- Antioxidant effect of organic purple grape juice on exhaustive exerciseApplied Physiology, Nutrition, and Metabolism, 2013
- Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolismJournal of Applied Physiology, 2012
- A memristor based on current-induced domain-wall motion in a nanostructured giant magnetoresistance deviceJournal of Applied Physics, 2012
- Protective Effects on Mitochondria and Anti-Aging Activity of Polysaccharides from Cultivated Fruiting Bodies ofCordyceps militarisThe American Journal of Chinese Medicine, 2010
- Immunostimulatory Effects ofCordyceps militarison Macrophages through the Enhanced Production of Cytokines via the Activation of NF-κBImmune Network, 2010
- Octacosanol Supplementation Increases Running Endurance Time and Improves Biochemical Parameters After Exhaustion in Trained RatsJournal of Medicinal Food, 2003
- Biochemical correlates of fatigueEuropean Journal of Applied Physiology, 1988