Immortal Time Bias in Observational Studies
Top Cited Papers
- 15 February 2021
- journal article
- editorial
- Published by American Medical Association (AMA) in JAMA
- Vol. 325 (7), 686-687
- https://doi.org/10.1001/jama.2020.9151
Abstract
This JAMA Guide to Statistics and Medicine explains immortal time bias, an error in estimating the association between an exposure and an outcome that results from misclassification or exclusion of time intervals; explains how this misclassification or exclusion can occur; and presents approaches to minimize or avoid immortal time bias.This publication has 4 references indexed in Scilit:
- Association of Premature Natural and Surgical Menopause With Incident Cardiovascular DiseaseJAMA, 2019
- Specifying a target trial prevents immortal time bias and other self-inflicted injuries in observational analysesJournal of Clinical Epidemiology, 2016
- Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetesBMJ, 2010
- Immortal Time Bias in PharmacoepidemiologyAmerican Journal of Epidemiology, 2007