ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth

Abstract
These findings show that ZMYND8 is a new negative and intrinsic regulator of the innate immune response in breast tumor cells, and that ZMYND8 may be a possible target for antitumor immunotherapy.
Funding Information
  • Mary Kay Foundation (08-19)
  • HHS | NIH | National Cancer Institute (R01CA222393)
  • Cancer Prevention and Research Institute of Texas (RR140036)
  • Cancer Prevention and Research Institute of Texas (RP190358)
  • Susan G. Komen (CCR16376227)
  • Welch Foundation (I-1903-20190330)
  • HHS | NIH | National Institute of General Medical Sciences (R35GM124693)
  • HHS | NIH | National Institute on Aging (R01AG066166)
  • Cancer Prevention and Research Institute of Texas (RP170671)
  • Welch Foundation (I-1939-20160319)