Neural Basis of Somatosensory Spatial and Temporal Discrimination in Humans: The Role of Sensory Detection
- 24 August 2021
- journal article
- research article
- Published by Oxford University Press (OUP) in Cerebral Cortex
- Vol. 32 (7), 1480-1493
- https://doi.org/10.1093/cercor/bhab301
Abstract
While detecting somatic stimuli from the external environment, an accurate determination of their spatial and temporal properties is essential for human behavior. Whether and how detection relates to human capacity for somatosensory spatial discrimination (SD) and temporal discrimination (TD) remains unclear. Here, participants underwent functional magnetic resonance imaging scanning when simply detecting vibrotactile stimuli of the leg, judging their location (SD), or deciding their number in time (TD). By conceptualizing tactile discrimination as consisting of detection and determination processes, we found that tactile detection elicited activation specifically involved in SD within the right inferior and superior parietal lobules, 2 regions previously implicated in the control of spatial attention. These 2 regions remained activated in the determination process, during which functional connectivity between these 2 regions predicted individual SD ability. In contrast, tactile detection produced little activation specifically related to TD. Participants’ TD ability was implemented in brain regions implicated in coding temporal structures of somatic stimuli (primary somatosensory cortex) and time estimation (anterior cingulate, pre-supplementary motor area, and putamen). Together, our findings indicate a close link between somatosensory detection and SD (but not TD) at the neural level, which aids in explaining why we can promptly respond toward detected somatic stimuli.Funding Information
- Ministry of Science and Technology of Taiwan
- National Health Research Institutes (108-2410-H-002-110-MY2, 107-2314-B-002-073, 104-2314-B-002-044-MY3, NHRI-EX106-10615NC)
This publication has 93 references indexed in Scilit:
- Mapping multisensory parietal face and body areas in humansProceedings of the National Academy of Sciences of the United States of America, 2012
- Theta-Burst Stimulation-Induced Plasticity over Primary Somatosensory Cortex Changes Somatosensory Temporal Discrimination in Healthy HumansPLOS ONE, 2012
- Resting-State Functional Connectivity of the Medial Superior Frontal CortexCerebral Cortex, 2011
- A new neural framework for visuospatial processingNature Reviews Neuroscience, 2011
- Defining functional SMA and pre-SMA subregions in human MFC using resting state fMRI: Functional connectivity-based parcellation methodNeuroImage, 2010
- Neural representation of time in cortico-basal ganglia circuitsProceedings of the National Academy of Sciences of the United States of America, 2009
- Role of right posterior parietal cortex in maintaining attention to spatial locations over timeBrain, 2009
- Neural Correlates of Tactile Detection: A Combined Magnetoencephalography and Biophysically Based Computational Modeling StudyJournal of Neuroscience, 2007
- Neural Coding of Tactile Decisions in the Human Prefrontal CortexJournal of Neuroscience, 2006
- Image Distortion Correction in fMRI: A Quantitative EvaluationNeuroImage, 2002