Association of celiac disease in patients with multiple sclerosis in Tuscany
- 1 January 2020
- journal article
- research article
- Published by Sociedad Espanola de Patologia Digestiva (SEPD) in Revista Española de Enfermedades Digestivas
- Vol. 112 (6), 474-476
- https://doi.org/10.17235/reed.2020.6123/2018
Abstract
Background and study purpose: to describe the comorbidity of celiac disease among a large cohort of multiple sclerosis patients in Tuscany. Methods: the association of celiac disease among multiple sclerosis adult patients (n=2050) was retrospectively evaluated. Results: 13 patients were diagnosed with celiac disease, the female:male ratio was 3.3:1 and the median age at diagnosis was 34.2 years (SD 13). Seventy-seven per cent of subjects complained about gastrointestinal symptoms. IgA anti- transglutaminase was positive in 85 % of cases and there was 70 % of villous atrophy. Conclusions: the frequency of celiac disease among multiple sclerosis patients examined was lower than in the general population (0.6 % vs 1 %) (p = 0.65).This publication has 12 references indexed in Scilit:
- Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten SensitivityThe American Journal of Gastroenterology, 2016
- European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac DiseaseJournal of Pediatric Gastroenterology and Nutrition, 2012
- Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteriaAnnals of Neurology, 2011
- The prevalence of celiac disease in Europe: Results of a centralized, international mass screening projectAnnals of Medicine, 2010
- Frequency of celiac disease is not increased among multiple sclerosis patientsMultiple Sclerosis Journal, 2008
- Headache and CNS white matter abnormalities associated with gluten sensitivityNeurology, 2001
- The histopathology of coeliac diseaseEuropean Journal of Gastroenterology & Hepatology, 1999
- Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and Nutrition.Archives of Disease in Childhood, 1990
- NEUROLOGICAL DISORDERS ASSOCIATED WITH ADULT CELIAC DISEASEBrain, 1966
- Gluten and Multiple SclerosisBMJ, 1965