Loss of the deubiquitinase OTULIN promotes hepatocellular carcinoma (HCC) in an mTOR-dependent manner
Open Access
- 30 March 2020
- journal article
- editorial
- Published by Springer Science and Business Media LLC in Cell Death & Differentiation
- Vol. 27 (5), 1455-1456
- https://doi.org/10.1038/s41418-020-0531-2
Abstract
No abstract availableThis publication has 12 references indexed in Scilit:
- OTULIN protects the liver against cell death, inflammation, fibrosis, and cancerPublished by Cold Spring Harbor Laboratory ,2019
- OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell deathEMBO Molecular Medicine, 2019
- Principles of Ubiquitin-Dependent SignalingAnnual Review of Cell and Developmental Biology, 2018
- Ubiquitin ligases in oncogenic transformation and cancer therapyNature Reviews Cancer, 2017
- The Met1-Linked Ubiquitin Machinery: Emerging Themes of (De)regulationMolecular Cell, 2017
- The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and AutoimmunityCell, 2016
- Ubiquitin signaling in immune responsesCell Research, 2016
- Linear ubiquitination in immunityImmunological Reviews, 2015
- OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked PolyubiquitinCell, 2013