Drug carriers for oral delivery of peptides and proteins: accomplishments and future perspectives
- 1 February 2013
- journal article
- review article
- Published by Future Science Ltd in Therapeutic Delivery
- Vol. 4 (2), 251-265
- https://doi.org/10.4155/tde.12.143
Abstract
Effective formulation for peptide and protein delivery through the oral route has always been the critical effort with the advent of biotechnology. Stability, enzymatic degradation and ineffective absorption are common difficulties found for conventional dosage forms. As a result, new drug-delivery approaches are used to circumvent these limitations and enhance effective oral drug delivery. Some of these technologies have reached late stages of clinical trials and promising results will be available in the near future. This review covers, in general, the recent carriers reported in literature.Keywords
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