Association Between Statin Use at the Time of Intra-abdominal Surgery and Postoperative Adhesion-Related Complications and Small-Bowel Obstruction
- 1 February 2021
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Network Open
- Vol. 4 (2), e2036315
- https://doi.org/10.1001/jamanetworkopen.2020.36315
Abstract
More than 90% of patients develop adhesions after intra-abdominal surgery.1,2 Adhesion-related complications (ARCs) occur in up to 5% of patients undergoing these operations and are responsible for significant morbidity and mortality. More than 70% of small-bowel obstructions (SBOs) and 40% of cases of infertility are secondary to adhesions.3-5 Future operations in patients with adhesions are associated with inadvertent enterotomy rates of 10% to 20%, resulting in an estimated mortality of 13%.6Keywords
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