Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits
Open Access
- 29 March 2023
- journal article
- research article
- Published by eLife Sciences Publications, Ltd in eLife
Abstract
Background: Causality between plasma triglyceride (TG) levels and atherosclerotic cardiovascular disease (ASCVD) risk remains controversial despite more than four decades of study and two recent landmark trials, STRENGTH and REDUCE-IT. Further unclear is the association between TG levels and non-atherosclerotic diseases across organ systems.Funding Information
- National Institute of General Medical Sciences (R35-GM124836)
- National Heart, Lung, and Blood Institute (R01-HL139865)
- National Heart, Lung, and Blood Institute (R01-HL155915)
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