Efficacy of a Combination of Conservative Therapies vs an Education Comparator on Clinical Outcomes in Thumb Base Osteoarthritis

Abstract

Osteoarthritis is the most common chronic joint disorder, with increasing prevalence particularly owing to increased longevity.^1,2 It most commonly affects the hands, among which first carpometacarpal joint (thumb base) osteoarthritis represents a particular clinical challenge because of its significant effect on hand function and limited evidence for efficacious treatments. Thumb base osteoarthritis predominantly affects postmenopausal women. Radiographic signs of osteoarthritis are estimated in approximately one-third of women older than 70 years,³ while approximately 1 in 20 have visited a medical professional because of thumb base pain.⁴