The study was aimed to assess culturable bacterial endophytes from the medicinal plant Aloe vera, their antimicrobial spectra against pathogens, and the potential of bacterial endophytes in textile and paper dyeing. Culturable seventeen bacterial endophytes were isolated from the Aloe vera plant out of which 16 showed varied antimicrobial activity against both human pathogens i.e., bacteria & fungi E. coli, S. pyogenes, acne bacterial isolate (ABI), A. niger, and F. oxysporum. Simultaneously, the bacterial endophyte ENDB3 is producing extracellular green-brown color pigment under submerged (SmF) condition and the extracted pigment has shown promising results in textile and paper dyeing at lab scale without using mordant. All the bacterial endophytes showed resistance against standard antibiotics (penicillin G P(10 units), Oxacillin (1 mcg), Cephalathin (30 mcg), Clindamycin (2 mcg), Erythromycin (15 mcg), and Amoxyclav (30 mcg)) at the specific concentration used. Concludingly, bacterial endophyte ENDB3 is found capable to produce bioactive molecules with pharmaceutical and dyeing industries which may provide a new path in the pursuit of new biological sources of drug and natural dyeing candidates. Hence, we suggest further evaluation and characterization of their bioactive molecules for pharmacological and dyeing potential.