Abstract
Objective – to summarize the various hypotheses regarding the development of Trigeminal Neuralgia with a brief discussion about the causes for its co-existence with Glossopharyngeal Neuralgia, which has been seen infrequently. Summary of background - Cranial nerve neuralgia is one of the most common pain syndromes attributed to the extreme (extremely) detrimental effects on middle age population who are more productive. The first documentation of Trigeminal neuralgia (TN) dates back second century AD by Aretaeus of Cappadocia, a contemporary of Galen.1 A study conducted from 1992 to 2002 in the UK reported an incidence of 26 per 100000 population per year.2 Its incidence is more prevalent amongst (the) female population with the ratio of 1.7:1, and increases with the age. The purpose of my paper is to summarise all the possible mechanisms that lead to the development of Trigeminal neuralgia and to create an update regarding what we know about it now. My paper would also like to explore certain possibilities, which according to me, is (are) responsible for its infrequent occurrence with Glossopharyngeal neuralgia.