Metachronous Synovial Sarcoma After Treatment of Mixed Germ Cell Tumor in a Child with Complete Gonadal Dysgenesis
Open Access
- 27 February 2018
- journal article
- research article
- Published by Galenos Yayinevi in Journal of Clinical Research in Pediatric Endocrinology
- Vol. 10 (1), 87-90
- https://doi.org/10.4274/jcrpe.4905
Abstract
Patients with complete XY gonadal dysgenesis (GD) show a high predisposition to germ cell tumors (GCT). Patients with coexistence of GCT and GD have been reported previously. Here we present a 15-year-old girl with mixed GCT and GD who also developed an intra-abdominal synovial sarcoma one year after the treatment. This is the first report, to our knowledge, of synovial sarcoma associated with XY GD.Keywords
This publication has 22 references indexed in Scilit:
- Swyer syndromeCurrent Opinion in Endocrinology, Diabetes and Obesity, 2014
- Teratoma with malignant transformation: report of three cases and review of the literatureClinical Imaging, 2014
- Review and management of 46,XY Disorders of Sex DevelopmentJournal of Pediatric Urology, 2013
- Secondary Leukemia Associated with the Anti-Cancer Agent, Etoposide, a Topoisomerase II InhibitorInternational Journal of Environmental Research and Public Health, 2012
- Coexistence of a Choriocarcinoma and a Gonadoblastoma in the Gonad of a 46,XY Female: A Single Nucleotide Polymorphism Array AnalysisPediatric and Developmental Pathology, 2010
- Swyer syndrome: presentation and outcomesBJOG: An International Journal of Obstetrics and Gynaecology, 2008
- Tumors of dysgenetic gonads in Swyer syndromeJournal of Pediatric Surgery, 2007
- Gonadoblastomas in 5 Patients with 46,XY Gonadal DysgenesisExperimental and Clinical Endocrinology & Diabetes, 2005
- Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issuesLaboratory Investigation, 2005
- SRY Mutation and Tumor Formation on the Gonads of XY Pure Gonadal Dysgenesis PatientsCancer Genetics and Cytogenetics, 1999