Abstract: Advancement in medical science has always been one of the most vital aspects of the human race. With the progress in technology, the use of modern techniques and equipment is always imposed on treatment purposes. Nowadays, machine learning techniques have widely been used in medical science for assuring accuracy. In this work, we have constructed computational model building techniques for liver disease prediction accurately. We used some efficient classification algorithms: Random Forest, Perceptron, Decision Tree, K-Nearest Neighbors (KNN), and Support Vector Machine (SVM) for predicting liver diseases. Our works provide the implementation of hybrid model construction and comparative analysis for improving prediction performance. At first, classification algorithms are applied to the original liver patient datasets collected from the UCI repository. Then we analyzed features and tweaked to improve the performance of our predictor and made a comparative analysis among the classifiers. We examined that, KNN algorithm outperformed all other techniques with feature selection.