Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
Open Access
- 13 October 2021
- journal article
- Published by Heighten Science Publications Corporation in Journal of Pulmonology and Respiratory Research
- Vol. 5 (1), 097-105
- https://doi.org/10.29328/journal.jprr.1001033
Abstract
The objective was to assess the antioxidant effect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant effect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below.Keywords
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